Monday, January 20, 2014

Consciousness As Part of the Cosmos



An excellent review and discussion of one of the most exciting and controversial theories of Consciousness.

Consciousness in the universe: A review of the ‘Orch OR’ theory

  • a Anesthesiology, Psychology and Center for Consciousness Studies, The University of Arizona, Tucson, AZ, USA
  • b Mathematical Institute and Wadham College, University of Oxford, Oxford, UK

Abstract

The nature of consciousness, the mechanism by which it occurs in the brain, and its ultimate place in the universe are unknown. We proposed in the mid 1990ʼs that consciousness depends on biologically ‘orchestrated’ coherent quantum processes in collections of microtubules within brain neurons, that these quantum processes correlate with, and regulate, neuronal synaptic and membrane activity, and that the continuous Schrödinger evolution of each such process terminates in accordance with the specific Diósi–Penrose (DP) scheme of ‘objective reduction’ (‘OR’) of the quantum state. This orchestrated OR activity (‘Orch OR’) is taken to result in moments of conscious awareness and/or choice. The DP form of OR is related to the fundamentals of quantum mechanics and space–time geometry, so Orch OR suggests that there is a connection between the brainʼs biomolecular processes and the basic structure of the universe. Here we review Orch OR in light of criticisms and developments in quantum biology, neuroscience, physics and cosmology. We also introduce a novel suggestion of ‘beat frequencies’ of faster microtubule vibrations as a possible source of the observed electro-encephalographic (‘EEG’) correlates of consciousness. We conclude that consciousness plays an intrinsic role in the universe.

Highlights

The Orch OR theory proposes quantum computations in brain microtubules account for consciousness.
Microtubule ‘quantum channels’ in which anesthetics erase consciousness are identified.
Evidence for warm quantum vibrations in brain microtubules is cited.
Interference of microtubule vibrations are ‘beat frequencies’ seen as EEG.
Orch OR links consciousness to processes in fundamental space–time geometry.

Potential Neuroscience Breakthrough

Chronometric Electrical Stimulation of Right Inferior Frontal Cortex Increases Motor Braking

  1. Nitin Tandon2,3

http://www.jneurosci.org/content/33/50/19611.short?sid=74bee42e-deee-43c6-8227-5c8aed06b44f

If this study is replicated, it could be a major breakthrough in neuroscience, permitting clarification of the commonly misunderstood distinction among feelings, impulses and behaviors--a major problem in psychiatric treatment of "irresistible impulses," commonly seen in most mental health disorders, (intrusive, unwanted thoughts and feelings), but often inappropriately diagnosed. Examples include obsessive worry, self-criticism, and anger resulting in aggressive behavior designed to hide more vulnerable feelings from ourselves and others. Most people use the words anger and aggression interchangeably, despite the reality that anger is a feeling and aggression is a behavior. We often hear patients describe their aggressive behavior as a "necessary" outcome of their feelings of anger, denying that the behavior was "chosen." This is often better understood when one realizes that the feelings of anger are usually "used" to hide from ourselves, more vulnerable feelings, such as helplessness, shame, abandonment, or other feelings of being hurt. Once the neuro-circuitry is elaborated, trans-cranial magnetic stimulation, pharmaceutical or neutraceutical (eg. N-Acetylcysteine, NAC) modification together with effective psychotherapeutic reframing of thoughts and feelings content, could replace the electricity-induced model. Because of neurons' plasticity, many of these modalities, including effective psychotherapy alone, have been postulated to produce neurogenesis and the replacement of unwanted connections with more desirable tracts, often resulting in apoptotic removal of the undesirable tracts. If confirmed in peer reviewed research, this study should be considered a ground-breaking accomplishment. 


Ange Lobue, MD, MPH, BSPharm
American Board of Psychiatry & Neurology
Academy of Television Arts & Sciences
5244 Patrick Creek Drive
McKinleyville, CA